H1-Antihistamines and itch in atopic dermatitis
نویسندگان
چکیده
منابع مشابه
Itch in atopic dermatitis - pathophysiology and treatment.
Pruritus is an essential feature of atopic dermatitis with a high impact on the quality of life. Although the pathophysiology of atopic dermatitis itch is not fully understood, recent studies have demonstrated that a variety of mechanisms contribute to the induction and maintenance of the symptom. For example, an increased number of cutaneous nerve fibers and neuropeptides were identified in at...
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Atopic dermatitis is a common skin disease with high morbidity and is associated with severe itch and chronic skin inflammation. In this issue of Cell, Wilson et al. demonstrate that epithelial cells communicate directly with cutaneous sensory neurons via a cytokine to induce itch.
متن کاملAtopic dermatitis: addressing allergy, infection, itch and complementary therapies.
Atopic dermatitis (AD) is a complex condition that results from the dynamic interplay between genetic predisposition, skin barrier defects, environmental factors, and a dysfunctional immune system. As a result, AD can be complicated by irritant and allergic contact dermatitis and imbalances in the skin microbiome, which can subsequently exacerbate the severity and complicate the course of preex...
متن کاملBrain Processing of Contagious Itch in Patients with Atopic Dermatitis
Several studies show that itch and scratching cannot only be induced by pruritogens like histamine or cowhage, but also by the presentation of certain (audio-) visual stimuli like pictures on crawling insects or videos showing other people scratching. This phenomenon is coined "Contagious itch" (CI). Due to the fact that CI is more profound in patients with the chronic itchy skin disease atopic...
متن کاملClinical aspects of itch in adult atopic dermatitis patients.
Although pruritus is an essential symptom of atopic dermatitis, its complex pathomechanism is not fully understood. The aim of this study was to characterize the clinical pattern of itch in adult subjects with atopic dermatitis. A total of 89 patients (59 females, 30 males) with atopic dermatitis, age range 18-60 years, were included in the study. Each patient completed a questionnaire about cl...
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ژورنال
عنوان ژورنال: Experimental Dermatology
سال: 2015
ISSN: 0906-6705
DOI: 10.1111/exd.12626